== Biopunk == ==== DIY Scientists Hack the Software of Life ==== ==== Marcus Wohlsen 2011 Beaverton Library 660.6 WOH ==== This book is interesting, but it has not aged well. Wohlsen is busy with non-writing projects, perhaps he can find a collaborator to rewrite a second edition, . index and notes . [[ http://parts.igem.org/Main_Page | Registry of Standard Biological Parts ]] . p006 vaccines made without millions of chicken eggs, Scientific American 2004 [[ https://www.scientificamerican.com/article/better-flu-vaccine/ | more recent ]] . p010 [[ https://en.wikipedia.org/wiki/2001_anthrax_attacks | 2001 anthrax attacks ]], likely perpetrator [[ https://en.wikipedia.org/wiki/United_States_Army_Medical_Research_Institute_of_Infectious_Diseases | USAMRIID ]] researcher [[ https://en.wikipedia.org//wiki/Bruce_Edwards_Ivins | Bruce Edwards Ivins ]] . p020 https://groups.google.com/group/diybio . p032 [[ https://www.theguardian.com/politics/2008/jul/15/past.margaretthatcher | one of only five non-royal British subjects ... state funeral ]] Guardian article mentions nine, [[ https://en.wikipedia.org/wiki/State_funerals_in_the_United_Kingdom | wikipedia ]] lists 13 . p041 [[ https://en.wikipedia.org/wiki/Itinerant_groups_in_Europe | Travellers in Ireland and Scotland ]] . p041 [[ https://en.wikipedia.org/wiki/Meredith_L._Patterson | Meredith L. Patterson ]] https://maradydd.livejournal.com/496085.html | Biopunk Manifesto ]] . p046 [[ http://diybio.org/2009/03/20/extract-dna-from-strawberries | extracting DNA from strawberries ]] . p051 [[ https://en.wikipedia.org/wiki/ELISA | ELISA ]] enzyme-linked immunosorbent assay . p053 [[ https://cyber.harvard.edu/wealth_of_networks/Main_Page | The Wealth of Networks ]] . p062 pearlbiotech.com [[ https://en.wikipedia.org/wiki/Gel_electrophoresis | gel boxes ]], seemingly gone 2017 . p065 [[ https://openpcr.org | OpenPCR ]] thermocycler . p072 Navbharat 151, Monsanto BT seed, Gujarati farmers crossed with other varieties to produce even better seed . p077 2010, judge throws out Myriad Genetics patents on BRCA1 and BRCA2 genes (related to breast cancer) . p078 [[ https://content.time.com/time/subscriber/article/0,33009,914901,00.html | April 1977 Doomsday Tinkering with life ]] . p084 [[ https://en.wikipedia.org/wiki/Andrew_Hessel | Andrew Hessel ]] [[ https://web.archive.org/web/20190221221359/http://pinkarmy.org/ | Pink Army Cooperative ]], seemingly hijacked in 2020 . p100 Aubrey de Grey, '''dead links:''' [[ http://www.technologyreview.com/biomedicine/15936/page1/ | scathing review ]] [[ http://www.technologyreview.com/biomedicine/15941/?a=f | response ]] . probable links: [[ https://doi.org/10.1038/sj.embor.7400555 | Science fact and the SENS agenda ]] . de Grey response: [[ https://www.embopress.org/doi/10.1038/sj.embor.7400565 | Like it or not, life-extension research extends beyond biogerontology ]] . p102 [[ https://about.me/erigentry | Eri Gentry ]] [[ https://biocurious.org/ | BioCurious ]] . p105 John Schloendorn meets researcher willing to share research cancer cells. He calls Eri Gentry from a Subway sandwich shop "Eri, Eri, I'm so excited! I have colon and prostate cancer!", disturbing other customers. . p111 https://www.meetup.com/BioCurious/ . p123 [[ https://en.wikipedia.org/wiki/Grim_Sleeper | Grim Sleeper serial killer ]] traced through son's DNA . p123 cost of human genome sequence will close in on zero - no, the [[ https://www.genome.gov/sites/default/files/inline-images/2021_Sequencing_cost_per_Human_Genome.jpg | cost ]] dived three orders of magnitude between 2006 ( $10M ) and 2011 ( $10K ), but has gone down "only" 20X (to $500 or so) by 2021, 35% per year. On the same graph, Moore's Law is depicted as a straight line 1000x drop in 20 years, 41% per year, 2x per 2 years. Both are impressive improvements, and they will likely continue, but trees do not grow to the sky, and most trendlines hit physical limits eventually. . p130 F Raymond !McCauley . p138 Folic Acid B₉, MTHFR gene, homocystinuria . p140 different folic acid vitamin ( [[ https://www.drugs.com/mtm/l-methylfolate.html | L-methylfolate ]]? )for people with absorption troubles . p141 [[ https://www.snpedia.com/ | SNPedia ]] [[ https://promethease.com/ | Promethease ]] . p143 [[ https://web.archive.org/web/20090105205441/http://mrgene.com | mrgene.com ]] dead link . p144 J. Chris Anderson in Stanley Hall at UCB (not the TED guy or the Wired editor) . p148 [[ https://sourceforge.net/projects/clothocad/ | Clotho synthetic biology software ]] (clothocad.org in notes NFG ) . p150 [[ https://www.storeitcold.com/ | CoolBot ]] . p152 [[ https://igem.org/ | iGEM BioBricks ]] . p155 [[ https://web.archive.org/web/20130724165008/http://www.biofab.org:80/ | biofab ]] dead link after 2013 . p156 [[ https://en.wikipedia.org//wiki/Mycoplasma_laboratorium | Synthia ]] ''subset'' of Mycoplasma mycoides, JVC1-syn3.0 . p158 [[ https://rootbridges.blogspot.com | Living Root Bridges ]] . p159 [[ https://en.wikipedia.org/wiki/Artemisinin | Artemisisin ]] antimalarial drug extracted from Artemisia annua herb around 1980. Market price varies wildly. Synthesized in 2006, marketed by Sanofi in 2014, goal is to tackle a disease that kills 500K people per year. Wohlson whinges about reduced income to farmers ... but what about the millions of lives saved per decade by a stable and affordable supply of life-saving medicine? . p167 2004, art professor Steve Kurtz arrested and prosecuted for years because of a molecular biology art exhibit. . p169 2008, government indictment dismissed by federal judge as "insufficient on its face". . p179 FBI's [[ https://www.aiche.org/sbe/community/bio/edward-you | Edward You ]], Special Agent Bioterrorism Prevention, arranges booth at [[ https://en.wikipedia.org/wiki/International_Genetically_Engineered_Machine | iGEM 2009 ]] and the 2010 [[ https://newsroom.ucla.edu/magazine/synthetic-biology-diy-science | Outlaw Biology conference ]] . p180 Eric Drexler gray goo, [[ https://web.archive.org/web/20110711090940/http://nanotechweb.org/cws/article/indepth/19648 | later disvowed. ]] . p195 [[ https://www.nybooks.com/articles/2007/07/19/our-biotech-future/ | Freeman Dyson optimism ]] . p207 [[ https://backyardbrains.com/ | Backyard Brains ]] [[ https://www.amazon.com/dp/0262544385 | How Your Brain Works ]]