The End of Plagues
Multco Central . 362.19691 R476e . 2013
Forward by Sir Richard Sykes
- p001 Introduction
- p005 Ch01 . The Power of the Invisible
p006 Bubonic plague killed 1/3 of European population between 1348 and 1350
p006 Great Plague of London 1665-1666
p008 Ramses V died of smallpox in "1157 BC" (wp 1144 BC)
- p011 Ch02 . Circassian Beauties and Pioneering Women
p012 Variola major mutated from Variola minor between 400 and 1600 years ago
p013 Lady Mary Wortley Montagu née Pierrepont smallpox at 26, championed variolation
p014 Circassian beauty
p014 variolation
p017 Scottish surgeon Charles Maitland innoculated Newgate prisoners in 1722, all survived and were pardoned
p018 Cotton Mather learned of variolation from slave Onesimus
- p019 Boston doctor Zabdiel Boylston innoculed 242 people during 1721 smallpox outbreak
- p019 smallpox mortality 10% to 30%
- p019 variolation morality 17 out of 897, 2%
p020 French medical establishment opposed, Voltaire in favor
- p020 Dr. Robert Sutton improved procedure, son Daniel Sutton inoculated 40,000 with 5 deaths
p021 Thomas Dimsdale
p021 Catherine the Great innoculated by Thomas Dimsdale, rewarded with "Baron of the Russian Empire"
p023 Ch03 The Making of Jenner
p023 Edward Jenner
p024 Jenner lodged with surgeon John Hunter
- p026 Jenner found foreign seed in birds, evidence for bird migration
- p026 Jenner observed newly hatched cuckoos push other chicks and eggs out of nest
p027 observed narrowing and calcification in coronary arteries of angina patients
- p029 Ch 4 Why Not Try the Experiment?
p095 bacteriologist Albert Calmette 1863-1933 and veterinarian Camille Guerine 1872-1961
p095 passaging (pronounced pasarging) tuberculosis bacteria 1908 until 1919
p095 Bacillus Calmette–Guérin (BCG) vaccine tested in humans 1921, 500K infants safely vaccinated
- p095 240 babies vaccinated in Lübeck, all developed acute tuberculosis, 72 died
- p096 Lübeck BCG contaminated with virulent bacillus grown in the same incubator
p098 six-needle Heaf gun