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Sangreeta Bhatia, iron oxide nanoparticles (what size???) attached to proteins that bind to cancer blood vessel proteins, encapsulated n PEG (polyethylene glycol) shield, with a protein cut by [[ http:doi.org/10.1073/pnas0610298104 | tissue specific enzymes (2016) ]] [[ http://doi.org/10.1016/j.biomaterials.2009.10.012 | (2019) ]] that causes the nanoparticles bind to each other and cluster near "cancer enzymes" that cancer cells use to open up spaces in normal tissues. This led to fluorescent proteins that can be activated by cancer enzymes and appear in urine [[ http:doi.org/10.1073/pnas1314651111 | (2014) ]], [[ https://www.glympsebio.com/ | Glympse Bio ]]. Sangreeta Bhatia, iron oxide nanoparticles (what size???) attached to proteins that bind to cancer blood vessel proteins, encapsulated n PEG (polyethylene glycol) shield, with a protein cut by [[ http://doi.org/10.1073/pnas0610298104 | tissue specific enzymes (2016) ]] [[ http://doi.org/10.1016/j.biomaterials.2009.10.012 | (2019) ]] that causes the nanoparticles bind to each other and cluster near "cancer enzymes" that cancer cells use to open up spaces in normal tissues. This led to fluorescent proteins that can be activated by cancer enzymes and appear in urine [[ http:doi.org/10.1073/pnas1314651111 | (2014) ]], [[ https://www.glympsebio.com/ | Glympse Bio ]].

The Age of Living Machines

Susan Hockfield PhD, BvtnLib 660.6 HOC, 2019


Good book. It would be better if it wasn't shoehorned into the "episode visit interview chapter" style common to most recent science journalist books. Perhaps this is "inspiring writing partner" Toby Lester's work.

Hockfield is a professor of neuroscience and MIT president emerita (2004-2012).

The "nanoparticle" buzzword appears frequently; measurements rarely, measurement errors never.

Angela Belcher, abalone shells calcium carbonate in fiber matrix),

  • p33 electric car battery manufacture 20 tonnes of carbon dioxide
  • p47 2006-2009 made button cells.
  • No information on watt-hours per gram or number of cycles, frustrating

Peter Agre, aquaporin, one pore is 3 billion water molecules per second

  • KHL A liter of water is 3e25 water molecules, so processing 1 liter per second requires more than 1e19 pores
  • Suggests using osmotic pressure to move water out of waste and into concentrated detergent
  • Aquaporin A/S 2005 Denmark: Peter Holme Jensen, Ostergaard Jensen, Claus Helix-Nielsen (Maribor Slovenia)
  • p68 embed membrane spheres in 200 nm membrane sheet on top of porous support sheet.
  • some (slow) water filter products

Sangreeta Bhatia, iron oxide nanoparticles (what size???) attached to proteins that bind to cancer blood vessel proteins, encapsulated n PEG (polyethylene glycol) shield, with a protein cut by tissue specific enzymes (2016) (2019) that causes the nanoparticles bind to each other and cluster near "cancer enzymes" that cancer cells use to open up spaces in normal tissues. This led to fluorescent proteins that can be activated by cancer enzymes and appear in urine (2014), Glympse Bio.

LivingMachines (last edited 2023-12-14 22:17:28 by KeithLofstrom)