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Pandora's Lab
Seven Stories of Science Gone Wrong
- Paul A. Offit, M.D. . 2017 . 500 OFFIT 2017 . Hillsboro Library
p001 Introduction
p015 Chapter 1 - God's Own Medicine
p022 Alexander Wood invented first hypodermic needle 1853 to administer morphine (rather than orally), believed that injection would "cure the appetite" for morphine addiction.
- "Pandora" repeats myth that morphine overdose injection killed his wife, who actually outlived him by 10 years.
p024 Heinrich Dreser responsible for aspirin and heroin and codeine at Bayer AG
p025 Eli Lilly "safe" heroin distributed over-the-counter without prescription in the US in 1900, JAMA "standard of care" in 1906
- p025 1906 JAMA: heroin standard of care for many respiratory ailments; by 1910 doctors aware of addiction, use declined
p027 next, thebaine a different opium compound. oxycodone the synthetic form in 1916,
p028 Purdue OxyContin time release tablet releases immediate addictive dose if chewed
p041 Chapter 2 - The Great Margarine Mistake
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p061 Chapter 3 - Blood From Air
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p097 Chapter 4 America's Master Race
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p131 Chapter 5 - Turning the Mind Inside Out
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p161 Chapter 6 - The Mosquito Liberation Front
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p191 Chapter 7 - Nobel Prize Disease
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p213 Chapter 8 - Learning From the Past
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- p241 Epilogue
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- p243 Acknowledgements
- p245 Selected Bibliography
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- p273 About the Author
- p275 Index
