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Pandora's Lab

Seven Stories of Science Gone Wrong

  • Paul A. Offit, M.D. . 2017 . 500 OFFIT 2017 . Hillsboro Library


  • p001 Introduction


  • p015 Chapter 1 - God's Own Medicine

  • p016 alpha-narcotine papaverine thebaine

  • p022 Alexander Wood invented first hypodermic needle 1853 to administer morphine (rather than orally), believed that injection would "cure the appetite" for morphine addiction.

    • "Pandora" repeats myth that morphine overdose injection killed his wife, who actually outlived him by 10 years.
  • p024 Heinrich Dreser responsible for aspirin and heroin and codeine at Bayer AG

  • p025 Eli Lilly "safe" heroin distributed over-the-counter without prescription in the US in 1900, JAMA "standard of care" in 1906

  • p025 1906 JAMA: heroin standard of care for many respiratory ailments; by 1910 doctors aware of addiction, use declined
  • p027 next, thebaine a different opium compound. oxycodone the synthetic form in 1916,

  • p028 Purdue OxyContin time release tablet releases immediate addictive dose if chewed


  • p041 Chapter 2 - The Great Margarine Mistake

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  • p061 Chapter 3 - Blood From Air

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  • p097 Chapter 4 America's Master Race

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  • p131 Chapter 5 - Turning the Mind Inside Out

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  • p161 Chapter 6 - The Mosquito Liberation Front

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  • p191 Chapter 7 - Nobel Prize Disease

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  • p213 Chapter 8 - Learning From the Past

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  • p241 Epilogue
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  • p243 Acknowledgements


  • p245 Selected Bibliography
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  • p273 About the Author


  • p275 Index

PandorasLab (last edited 2026-05-15 06:01:03 by KeithLofstrom)