Diff for "PandorasLab"

Differences between revisions 17 and 19 (spanning 2 versions)

Pandora's Lab

p015 Chapter 1 - God's Own Medicine
p016 alpha-narcotine papaverine thebaine
p022 Alexander Wood invented first hypodermic needle 1853 to administer morphine (rather than orally), believed that injection would "cure the appetite" for morphine addiction.
- "Pandora" repeats myth that morphine overdose injection killed his wife, who actually outlived him by 10 years.
p024 Heinrich Dreser responsible for aspirin and heroin and codeine at Bayer AG
p025 Eli Lilly "safe" heroin distributed over-the-counter without prescription in the US in 1900, JAMA "standard of care" in 1906
p025 1906 JAMA: heroin standard of care for many respiratory ailments; by 1910 doctors aware of addiction, use declined
p027 next, thebaine a different opium compound. oxycodone the synthetic form in 1916,
p028 Purdue OxyContin time release tablet releases immediate addictive dose if chewed

p041 Chapter 2 - The Great Margarine Mistake
p043 Ancel Keys urged fat restriction
po44 1977 McGovern report food guidelines authored by Nick Mottern non-scientist reporter
p048 conflated unhealthy saturated fats with healthy, essential unsaturated fats (some double bonds between carbons)
p050 margarine unhealthy trans-fats
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+ .p048 conflated unhealthy [[ https://en.wikipedia.org/wiki/Saturated_fat | saturated fats ]] with healthy, essential [[ https://en.wikipedia.org/wiki/Unsaturated_fat | unsaturated fats ]] (some double bonds between carbons)
 .p050 [[ https://en.wikipedia.org/wiki/Margarine | margarine ]] unhealthy [[ https://en.wikipedia.org/wiki/Trans_fat | trans-fats ]]
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