|
Size: 633
Comment:
|
Size: 637
Comment:
|
| Deletions are marked like this. | Additions are marked like this. |
| Line 1: | Line 1: |
| ## page was renamed from DimmockModernVirology | |
| Line 3: | Line 2: |
| ----- | ---- |
| Line 8: | Line 7: |
| ------- === Basic Virology, Wagner, 2008 === ---- |
Modern Virology, Dimmock, 2007
p139 s9.5 Herpesviruses HSV1: 70 genes, 153kbp
α immediate early phase β early γ late
p141: UL41 VHS = virion host shutoff. A ribonuclease that degrades cytoplasmic mRNA that is being translated. Decreases the half-life of all mRNA in the cell, favoring protein expression from viral genes that are being actively transcribed. Later, a more specific host shutoff function (what function???) is expressed, and UL41 is inactivated by binding to VP16.
Basic Virology, Wagner, 2008