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| == wiki.keithl.com/DanielGibbs == === A Tattoo on my Brain === |
=== wiki.keithl.com/DanielGibbs === = A Tattoo on my Brain = |
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| [[ | Daniel Gibbs ]] with [[ | Teresa H. Barker ]] | ~+[[ | Daniel Gibbs ]] with [[ https://search.worldcat.org/search?q=au%3D%22Barker%2C+Teresa%22&author=Barker%2C+Teresa%7CBarker+Teresa | Teresa H. Barker ]]+~ |
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| Also see [[ https://search.worldcat.org/title/1395425649 | Dispatches from the land of Alzheimer's ]] 2024 No mention, of pathogens, bacteria, viruses, herpes, as causal. Cholesterol is mentioned on page 47-48: "It's not as if the APOE gene is designed for destructive purposes: it's not. The APOE gene is the DNA blueprint for a specific lipoprotein, a protein that is involved in the transport of certain lipids in the blood. It comes in three variants, or alleles: APOE-2, APOE-3, and APOE-4. For reasons that are still not entirely clear, this gene for a protein involved in cholesterol transport also affects risk for acquiring Alzheimer's disease. It seems there is an effect on the protein beta-amyloid in the brain, but the mechanism of APOE-4 risk is probably more complicated. We just don't know yet what it is." .1x APOE-2 decreased risk .2x APOE-3 0.13x risk .1x APOE-4 3.0x risk .2x APOE-4 12.0x risk |
wiki.keithl.com/DanielGibbs
A Tattoo on my Brain
A Neurologist's Personal Battle against Alzheimer's Disease
Daniel Gibbs with Teresa H. Barker
Cedar Mill Library 616.8311 GIBBS
Also see Dispatches from the land of Alzheimer's 2024
No mention, of pathogens, bacteria, viruses, herpes, as causal.
Cholesterol is mentioned on page 47-48:
"It's not as if the APOE gene is designed for destructive purposes: it's not. The APOE gene is the DNA blueprint for a specific lipoprotein, a protein that is involved in the transport of certain lipids in the blood. It comes in three variants, or alleles: APOE-2, APOE-3, and APOE-4. For reasons that are still not entirely clear, this gene for a protein involved in cholesterol transport also affects risk for acquiring Alzheimer's disease. It seems there is an effect on the protein beta-amyloid in the brain, but the mechanism of APOE-4 risk is probably more complicated. We just don't know yet what it is."
- 1x APOE-2 decreased risk
- 2x APOE-3 0.13x risk
- 1x APOE-4 3.0x risk
- 2x APOE-4 12.0x risk